Clinical and Preclinical Studies in New Drug Development
Frontro Pharma is your most trusted clinical research company for clinical & preclinical studies in new drug development, preclinical drug trials. Call Us
We understand the significance of preclinical studies in new drug development. Frontro pharma work on turning groundbreaking scientific findings into life-saving treatments. We bridge the gap between discovery and successful clinical development by offering a tailored range of services to perfectly meet your needs. Our team of research scientists possesses extensive expertise in various therapeutic areas, allowing us to deliver pertinent results from our advanced preclinical research methods. These results will assist you in making informed decisions regarding your drug development pathway.
Why Choose Frontro Pharma for Your Preclinical drug trials and medical trials?
- Unparalleled Expertise: Our staff is comprised of experts in various fields and they have accomplished much across different diseases. We keep ourselves updated on current developments in preclinical research, randomized clinical trial so as to give you up-to-date facts and insights.
- Solutions Tailored to You: Our range of in vitro and in vivo models makes it possible for us to conduct preclinical and clinical trial monitoring and personalized studies which align seamlessly with your unique drug candidate and research aims.
- Meticulous Science, Unbowed Confidence: Our work is guided by the highest scientific principles and Good Laboratory Practice (GLP). We maintain the integrity and reliability of every piece of data generated through this rigorous approach making it possible for your desired drug candidate to progress with confidence.
- Agile Collaboration for Seamless Progress: As we all understand, flexibility as well as collaboration are essential aspects within the fast world of drug development. We also interact closely during study design processes thus allowing them fit their specific requirements as well as timelines.
- Dedicated Project Management: From initiation to completion there is always a dedicated project manager assigned to handle every aspect about such studies. Effective communication is therefore maintained throughout, while timely reporting is observed at all times.
Our Preclinical Expertise: A Multifaceted Approach
In Vitro Models: In vitro models present controlled environments where effects of a drug candidate can be studied upon individual cells or tissues. They are handy in the early stages of drug discovery, where its efficiency in relation to toxicity would be assessed quickly. Therefore at Frontro Pharma we use a number of in vitro models including;
- Cell Culture Assays: We evaluate the influence of drug candidates on cell viability, proliferation, differentiation and other cellular functions relevant to your target disease by using well-established cell lines.
- Biochemical Assays: Our team uses several biochemical assays to measure the activity of enzymes, receptors as well as other important cellular targets for your drug candidate. That way, we are able to determine how your drug interacts with the biological processes that underlie this particular ailment.
- High-Throughput Screening (HTS): Using HTS technology; it is possible for us to evaluate vast libraries of potential drugs against certain diseases thereby allowing us discover potentially new leads with high chances for success quickly.
In Vivo Models
In vivo models, which use laboratory animals, are indispensable for testing drug candidates in their entirety. For your particular needs, we have a wide range of in vivo models that include:
- Rodent Models: These are mice and rats and often used for clinical and preclinical studies more than any other laboratory animal type. They have well characterized genetic background, defined disease models and relatively short lifespans that expedite the process of drug development.
- Large Animal Models: Large animal models such as dogs, pigs or non-human primates may be required in some instances. Such models can generate important preclinical data on the safety and efficacy of your drug candidate in a species closer to humans.
- Disease-Specific Models: We have extensive experience developing and using disease-specific models of various conditions such as diabetes, cardiotoxicity, pulmonary toxicity among others so we can assess how effectively our drug might work for you under conditions closely resembling human diseases.
Histopathological and Immunohistochemical Assessments
Comprehensive histopathological and immunohistochemical evaluations constitute an essential part of our pre clinical testing and assessments. It is through these techniques that we visualize how your drug affects tissues/cells at microscopic levels.
- Histopathology: This method entails observing tissue samples with a microscope to spot any modifications in cell morphology or arches brought about by drugs.
- Immunohistochemistry: With this procedure antibodies are used to identify specific proteins within tissues. Through this procedure it is possible to study how your drug candidate affects definite cellular processes together with signaling pathways.
Thus combining these approaches gives us a complete understanding regarding both cellular and tissue safety/efficacy profile pertaining to your drug candidate.
Partnering with Frontro Pharma: Advancing Your Drug Development Journey
We at Frontro Pharma, clinical research company are devoted towards becoming your most trusted companion during this journey of pre-clinical drug development. Combining our scientific excellence and a coherent range of service this means we give you high quality data to enable decision making and progress of your drug candidate into clinical development stage.
Discuss your specific needs with us today and know how Frontro Pharma can help you bridge the gap between discovery and delivery. This way, we will help promising discoveries turn into life-saving medicines.
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